Endoglin anticorps (AA 342-586)
Aperçu rapide pour Endoglin anticorps (AA 342-586) (ABIN7193820)
Antigène
Voir toutes Endoglin (ENG) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- AA 342-586
-
Fonction
- CD105 Antibody
-
Purification
- Purified antibody
-
Immunogène
- Purified recombinant fragment of human CD105 (AA: 342-586) expressed in E. Coli.
-
Isotype
- IgG1
-
-
-
-
Indications d'application
-
ELISA: 1/10000
FCM: 1/200 - 1/400
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
- Endoglin (ENG)
-
Autre désignation
- CD105
-
Sujet
-
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
-
Poids moléculaire
- 70.6 kDa
-
UniProt
- P17813
Antigène
-